Individuals with Limited Sun Exposure: People who have limited exposure to sunlight due to factors such as living in regions with long winters, spending most of their time indoors, or consistently using sunscreen may have a higher risk of Vitamin D deficiency.
People with Darker Skin Pigmentation: Individuals with darker skin produce less Vitamin D upon exposure to sunlight compared to those with lighter skin. Consequently, people with darker skin may have a higher risk of Vitamin D deficiency, especially if they live in areas with limited sunlight.
Elderly Individuals: As people age, their skin becomes less efficient at synthesizing Vitamin D when exposed to sunlight. Additionally, older adults may spend more time indoors and have reduced dietary intake, further increasing their risk of Vitamin D deficiency.
Individuals with Obesity: Vitamin D is fat-soluble, and it can become sequestered in fat tissues, reducing its bioavailability. Therefore, people with obesity may have lower circulating levels of Vitamin D and may benefit from testing.
Patients with Malabsorption Disorders: Certain medical conditions, such as celiac disease, inflammatory bowel disease (IBD), cystic fibrosis, or bariatric surgery, can impair the absorption of Vitamin D from the diet or supplements, leading to deficiency.
People with Chronic Kidney Disease: Impaired kidney function can affect the conversion of Vitamin D into its active form, leading to decreased Vitamin D levels in the body.
Individuals with Hyperparathyroidism or Hypoparathyroidism: These conditions can disrupt calcium and Vitamin D metabolism, leading to abnormalities in Vitamin D levels.
Breastfed Infants: Breast milk is not a significant source of Vitamin D, and exclusively breastfed infants may require Vitamin D supplementation. Pediatricians may recommend testing to assess Vitamin D status in infants who are exclusively breastfed or have limited sun exposure.
People with Symptoms of Vitamin D Deficiency: Individuals experiencing symptoms suggestive of Vitamin D deficiency, such as fatigue, muscle weakness, bone pain, frequent infections, or depression, may benefit from testing to confirm the diagnosis.
Patients with Osteoporosis or Osteomalacia: Vitamin D plays a crucial role in bone health, and deficiency can lead to conditions such as osteoporosis or osteomalacia. Testing may be recommended for individuals with bone health concerns to assess Vitamin D status.
Pregnant and Lactating Women: Pregnant and lactating women have increased Vitamin D requirements to support fetal and infant development. Testing may be recommended to ensure adequate Vitamin D levels during pregnancy and breastfeeding.
People Taking Certain Medications: Some medications, such as anticonvulsants, glucocorticoids, antiretrovirals, or weight-loss medications, can interfere with Vitamin D metabolism and increase the risk of deficiency.